CHROMATOGRAPHY |   Syringe filters

Filtration of the sample to remove particulate matter can be performed through the use of easy-to-use syringe filters. With a female luer lock inlet and a male slip outlet, the syringe filter easily fits onto the end of the disposable syringe containing the sample. This connection can be further strengthened by using a luer lock tip syringe, creating a more secure connection that can withstand higher filtration pressure. The type of membrane varies in properties and should be selected based on the characteristics of the matrix and the solvent: CA - Cellulose Acetate, NY - Nylon, PTFE - Polytetrafluoroethylene, PES - Polyethersulfone, PVDF - Polyvinylidenefluoride, RC - Regenerated Cellulose, MCE - Mixed esters of Cellulose, PP - Polypropylene. The choice of porosity depends on the application and, in the case of HPLC, on the particle size of the column: 0.20 µm up to ≤3 µm, 0.45> 3 µm. The volume of the sample will determine the choice of diameter, ensuring that the filter is not overloaded: Ø 13 mm up to 10 ml - Ø 25 mm  up to 100 ml.